The laboratory has state-of-the-art imaging equipment:

    • A 9.4 Tesla, 30 cm bore research magnet equipped with a new Bruker console with Paravision 4.0 software update. The core’s staff members develop standard protocols, which users can execute with relatively little training. The scanner is capable of a variety of state-of-art experiments including echo-planar imaging, diffusion weighted imaging, magnetization transfer imaging, and very fast imaging for monitoring contrast media uptake.
    • A new Philips Achieva 1.5 Tesla scanner equipped for parallel imaging. Among the advantages offered by the Philips scanner are extremely fast imaging and specialized coils for breast, prostate, pelvis, and spine.
    • Almost all of the clinical research is performed on this scanner but two recently upgraded GE scanners are also available for research.
    The upgraded equipment and the new 9.4 Tesla console has expanded and improved the types of imaging offered by the facility. It now provides a wide variety of anatomic and functional images including:
    • Very high resolution (as high as 100 microns in plane) T1 and T2-weighted images
    • Diffusion and Diffusion Tensor images
    • Dynamic contrast enhanced MR images with high spatial and spectral resolution
    • Very high resolution EPSI for improved anatomic and functional imaging
    • Magnetization Transfer images
    • Spin – tagging and angiograph
    • A variety of fast imaging methods including echo-planar imaging and fast spin echo imaging.
    The laboratory also has:
    • A well equipped small-animal surgery and an electronics laboratory
    • A Molecular and Physiological Imaging laboratory in the Radiology Department that the core uses for molecular biology, cell culture, contrast agent development and preparation.
    • Physiological monitoring equipment that measures blood-pressure, ECG, temperature, and oxygen
    • A number of fast imaging computers and software for data analysis
    • Access to time on clinical imaging equipment in the Goldblatt facility, the Duchossois Center for Advanced Medicine (DCAM) and the Neurosciences Imaging Center.

    The MRIS Core Facility provides the following services:

    1. Scans of tissues
    2. Scans of cells
    3. Scans of materials
    4. Scans of animal models of cancer (ie: prostate, mammary, ovary, brain etc)
    5. Scans of animal models not involved with cancer (ie: cardiac, brain, pancreas, etc.)
    6. Scans of patients
    These scans provide the following information:
    1. Detailed 3-D anatomy
    2. Perfusion
    3. Capillary permeability
    4. Blood volume
    5. Energy metabolism
    6. Metabolic markers for cancer
    7. Measurements of the apparent diffusion constant
    8. T1, T2 measurements.
    We also provide a variety of veterinary services including:
    1. Preparation of animals for MRI experiments
    2. Anesthesia and respiration
    3. Physiological monitoring
    4. Catheter implantation
    5. Tumor implantation
    For MRI experiments we perform the scans for users when necessary and analyze data.